p-Toluenesulfonic Acid (p-TSA) Catalyzed Efficient Synthesis of bis(indolyl)methanes under Grindstone Method
نویسندگان
چکیده
منابع مشابه
p-Toluenesulfonic acid catalyzed rapid and efficient protocol for one-pot synthesis of α-amino nitriles
A simple, rapid and efficient practical method for one-pot synthesis of α-amino nitriles has been achieved by a threecomponent condensation of carbonyl compounds, amines and trimethylsilyl cyanide in the presence of p-toluenesulfonic acid (p-TsOH) as a catalyst at ambient temperature. Operational simplicity, economic consideration, high yield, short reaction time and low toxicity are the key fe...
متن کاملP-TSA catalyzed facile and efficient synthesis of polyhydroquinoline derivatives through hantzsch multi-component condensation.
A facile and efficient synthetic route to polyhydroquinolines has been developed via four-component condensation reactions of aldehydes, dimedone, ethyl acetoacetate and ammonium acetate in the presence of p-toluenesulfonic acid (p-TSA) catalyst in ethanol at ambient temperature through Hantzsch reaction. Simple work-up procedure, environmentally friendly, inexpensive and non-toxic catalyst, sh...
متن کاملHydrolysis of Proteins with p-Toluenesulfonic Acid
A new procedure for analyses for tryptophan in proteins and glycoproteins is described. The method utilizes ptoluenesulfonic acid as the catalyst for hydrolysis and the amino acid analyzer for the quantitative estimation of tryptophan. The hydrolysis of proteins is carried out in 3 N p-toluenesulfonic acid containing 0.2 % 3-(Z-aminoethyl)indole in evacuated sealed tubes at 110” for 22, 48, and...
متن کاملContinuous Synthesis of Oleyl Oleate in Supercritical Carbon Dioxide using Solid p-Toluenesulfonic Acid as Catalyst
Supercritical carbon dioxide (SC-CO2) was used as solvent to synthesize oleyl oleate as an analog of Jojoba oil from oleic acid and oleyl alcohol with high conversion (100%) of the acid into ester in a short time of 100 min. Utilizing a low cost solid catalyst, p-toluenesulfonic acid monohydrate (PTSA), the esterification reaction was performed, without any prior preparation step...
متن کاملSynthesis and optimization ring opening of monoepoxide linoleic acid using p-toluenesulfonic acid
Biolubricant base oils, 9,12-hydroxy-10,13-oleioxy-12-octadecanoic acid (HYOOA) was synthesized based on the esterification reaction of Monoepoxide linoleic acid 9(12)-10(13)-monoepoxy 12(9)-octadecanoic acid (MEOA) with oleic acid (OA) and catalyzed by p-Toluenesulfonic acid. The optimum conditions for the experiment using D-optimal design to obtain high yield% of 84.61, conversion% of 83.54 a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Pharmacology and Toxicology
سال: 2006
ISSN: 1816-496X
DOI: 10.3923/jpt.2006.585.590